Search on: AGRP PROTEIN 
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Descriptor English:   Agouti-Related Protein 
Descriptor Spanish:   Proteína Relacionada con Agouti 
Descriptor Portuguese:   Proteína Relacionada com Agouti 
Synonyms English:   AGRP Protein
AGRT Protein
Agouti Related Protein  
Tree Number:   D12.644.276.074
D12.776.467.074
D23.529.074
Definition English:   A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY. 
History Note English:   2008 (1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52759 
Unique Identifier:   D054369 

Occurrence in VHL:
 

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